Description: Use these calculators for clinical trials including superiority, equivalence and non-inferiority trials.
Link: Calculators for clinical trials
Who is this resource for: Clinical investigators, statisticians
Who created this resource: This site is run by sealed envelopeTM, a British company that provides access to online software applications for randomizing patients into clinical trials and recording their case report form data.
What does this resource offer:
This website provides on-line tools to estimate the sample size needed for a clinical trial. Sample size calculations are supported for the following trial designs and outcome types:
- Superiority, equivalence, non-inferiority trials for binary outcomes
- Superiority, equivalence, non-inferiority trials for continuous outcomes
The information required as input from the user is clearly identified, as is the output generated by the program. The program does not have a calculator for time-to-event outcomes. The calculator does not provide the option of calculating the power, only the sample size. However, the program clearly explains the difference between the different designs (superiority, equivalence, non-inferiority), and provides references and the citation for the service.